Mesenchymal stem cells and macrophages interact through IL-6 to promote inflammatory breast cancer in pre-clinical models

Inflammatory breast cancer (IBC) is a unique and deadly disease with unknown drivers. We hypothesized the inflammatory environment contributes to the IBC phenotype. We used an in vitro co-culture system to investigate interactions between normal and polarized macrophages (RAW 264.7 cell line), bone-...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wolfe, Adam R., Trenton, Nicholaus J, Debeb, Bisrat G., Larson, Richard, Ruffell, Brian, Chu, Khoi, Hittelman, Walter, Diehl, Michael, Reuben, Jim M, Ueno, Naoto T., Woodward, Wendy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347707/
https://ncbi.nlm.nih.gov/pubmed/27756885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12694
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