Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism

PURPOSE: We recently demonstrated that histone deacetylase (HDAC) inhibitors can “reprogram” differentiated triple-negative breast cancer cells to become quiescent stem-like cancer cells. We hypothesized that the metabolic state of such cells differs from that of their differentiated progeny. RESULT...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Debeb, Bisrat G., Lacerda, Lara, Larson, Richard, Wolfe, Adam R., Krishnamurthy, Savitri, Reuben, James M., Ueno, Naoto T., Gilcrease, Michael, Woodward, Wendy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053589/
https://ncbi.nlm.nih.gov/pubmed/27078845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8631
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