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c-Myc deregulation induces mRNA capping enzyme dependency

c-Myc is a potent driver of many human cancers. Since strategies for directly targeting c-Myc protein have had limited success, upstream regulators and downstream effectors of c-Myc are being investigated as alternatives for therapeutic intervention. c-Myc regulates transcription and formation of th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lombardi, Olivia, Varshney, Dhaval, Phillips, Nicola M., Cowling, Victoria H.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347691/
https://ncbi.nlm.nih.gov/pubmed/27756891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12701
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