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Membrane integration of an essential β-barrel protein prerequires burial of an extracellular loop

The Bam complex assembles β-barrel proteins into the outer membrane (OM) of Gram-negative bacteria. These proteins comprise cylindrical β-sheets with long extracellular loops and create pores to allow passage of nutrients and waste products across the membrane. Despite their functional importance, s...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Wzorek, Joseph S., Lee, James, Tomasek, David, Hagan, Christine L., Kahne, Daniel E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347601/
https://ncbi.nlm.nih.gov/pubmed/28223520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616576114
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