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Crystal structure of Aquifex aeolicus σ(N) bound to promoter DNA and the structure of σ(N)-holoenzyme
The bacterial σ factors confer promoter specificity to the RNA polymerase (RNAP). One alternative σ factor, σ(N), is unique in its structure and functional mechanism, forming transcriptionally inactive promoter complexes that require activation by specialized AAA(+) ATPases. We report a 3.4-Å resolu...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347599/ https://ncbi.nlm.nih.gov/pubmed/28223493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619464114 |
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