Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain

Human Mas-related G protein-coupled receptor X1 (MRGPRX1) is a promising target for pain inhibition, mainly because of its restricted expression in nociceptors within the peripheral nervous system. However, constrained by species differences across Mrgprs, drug candidates that activate MRGPRX1 do no...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Li, Zhe, Tseng, Pang-Yen, Tiwari, Vinod, Xu, Qian, He, Shao-Qiu, Wang, Yan, Zheng, Qin, Han, Liang, Wu, Zhiping, Blobaum, Anna L., Cui, Yiyuan, Tiwari, Vineeta, Sun, Shuohao, Cheng, Yingying, Huang-Lionnet, Julie H. Y., Geng, Yixun, Xiao, Bo, Peng, Junmin, Hopkins, Corey, Raja, Srinivasa N., Guan, Yun, Dong, Xinzhong
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
PNAS Plus
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347560/
https://ncbi.nlm.nih.gov/pubmed/28223516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615255114
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