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Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
Vascular endothelial growth factor (VEGF) and its receptors have been implicated as key factors in tumor angiogenesis that are up-regulated by hypoxia. We evaluated the effects of DNA-binding small molecules on hypoxia-inducible transcription of VEGF. A synthetic pyrrole-imidazole polyamide designed...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC534742/ https://ncbi.nlm.nih.gov/pubmed/15556999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407617101 |
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