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Synthesis of galmic: A nonpeptide galanin receptor agonist

Galanin is a neuropeptide with a wide variety of biological functions. Few nonpeptide ligands, capable of activating galanin receptors, are available today. Based on known pharmacophores of galanin and the tripeptidomimetic galnon, a combinatorial library was formulated, synthesized, and screened ag...

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Main Authors: Ceide, Susana Conde, Trembleau, Laurent, Haberhauer, Gebhard, Somogyi, Laszlo, Lu, Xiaoying, Bartfai, Tamas, Rebek, Julius
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC534730/
https://ncbi.nlm.nih.gov/pubmed/15557002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407543101
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