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Bicodon bias can determine the role of synonymous SNPs in human diseases

BACKGROUND: For a long time synonymous single nucleotide polymorphisms were considered as silent mutations. However, nowadays it is well known that they can affect protein conformation and function, leading to altered disease susceptibilities, differential prognosis and/or drug responses, among othe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Genomics
Prif Awduron: McCarthy, Christina, Carrea, Alejandra, Diambra, Luis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347174/
https://ncbi.nlm.nih.gov/pubmed/28288557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3609-6
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