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Bicodon bias can determine the role of synonymous SNPs in human diseases

BACKGROUND: For a long time synonymous single nucleotide polymorphisms were considered as silent mutations. However, nowadays it is well known that they can affect protein conformation and function, leading to altered disease susceptibilities, differential prognosis and/or drug responses, among othe...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: McCarthy, Christina, Carrea, Alejandra, Diambra, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347174/
https://ncbi.nlm.nih.gov/pubmed/28288557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3609-6
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