On the mechanism and biology of cytochrome oxidase inhibition by nitric oxide
The detailed molecular mechanism for the reversible inhibition of mitochondrial respiration by NO has puzzled investigators: The rate constants for the binding of NO and O(2) to the reduced binuclear center Cu(B)/a(3) of cytochrome oxidase (COX) are similar, and NO is able to dissociate slowly from...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534717/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15546991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0405368101 |
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