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Roles of copper and a conserved aspartic acid in the autocatalytic hydroxylation of a specific tryptophan residue during cysteine tryptophylquinone biogenesis
The first posttranslational modification step in the biosynthesis of the tryptophan-derived quinone cofactors is the auto-catalytic hydroxylation of a specific Trp residue at the C-7 position on the indole side-chain. Subsequent modifications are catalyzed by modifying enzymes, but the mechanism by...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347147/ https://ncbi.nlm.nih.gov/pubmed/28140566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01137 |
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