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Enhanced osteogenesis and angiogenesis by mesoporous hydroxyapatite microspheres-derived simvastatin sustained release system for superior bone regeneration

Biomaterials with both excellent osteogenic and angiogenic activities are desirable to repair massive bone defects. In this study, simvastatin with both osteogenic and angiogenic activities was incorporated into the mesoporous hydroxyapatite microspheres (MHMs) synthesized through a microwave-assist...

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Publicado en:Sci Rep
Autores principales: Yu, Wei-Lin, Sun, Tuan-Wei, Qi, Chao, Zhao, Hua-Kun, Ding, Zhen-Yu, Zhang, Zhi-Wang, Sun, Ben-Ben, Shen, Ji, Chen, Feng, Zhu, Ying-Jie, Chen, Dao-Yun, He, Yao-Hua
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347005/
https://ncbi.nlm.nih.gov/pubmed/28287178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44129
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