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Enhanced osteogenesis and angiogenesis by mesoporous hydroxyapatite microspheres-derived simvastatin sustained release system for superior bone regeneration

Biomaterials with both excellent osteogenic and angiogenic activities are desirable to repair massive bone defects. In this study, simvastatin with both osteogenic and angiogenic activities was incorporated into the mesoporous hydroxyapatite microspheres (MHMs) synthesized through a microwave-assist...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yu, Wei-Lin, Sun, Tuan-Wei, Qi, Chao, Zhao, Hua-Kun, Ding, Zhen-Yu, Zhang, Zhi-Wang, Sun, Ben-Ben, Shen, Ji, Chen, Feng, Zhu, Ying-Jie, Chen, Dao-Yun, He, Yao-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347005/
https://ncbi.nlm.nih.gov/pubmed/28287178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44129
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