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Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells

Aims: Microglial cells are brain-resident macrophages engaged in surveillance and maintained in a constant state of relative inactivity. However, their involvement in autoimmune diseases indicates that in pathological conditions microglia gain an inflammatory phenotype. The mechanisms underlying thi...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Palmieri, Erika M., Menga, Alessio, Lebrun, Aurore, Hooper, Douglas C., Butterfield, D. Allan, Mazzone, Massimiliano, Castegna, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346956/
https://ncbi.nlm.nih.gov/pubmed/27758118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6715
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