Maturation of oxycodone pharmacokinetics in neonates and infants: Oxycodone and its metabolites in plasma and urine

AIMS: This study aimed to characterize the pharmacokinetics of oxycodone and its major metabolites in infants and covered the age range between extremely preterm neonates and 2‐year‐old infants. METHODS: Seventy‐nine infants (gestational age 23–42 weeks; postnatal age 0–650 days) received intravenou...

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Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Kokki, Merja, Heikkinen, Marja, Välitalo, Pyry, Hautajärvi, Heidi, Hokkanen, Juho, Pitkänen, Hanna, Sankilampi, Ulla, Ranta, Veli‐Pekka, Kokki, Hannu
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Pharmacokinetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346866/
https://ncbi.nlm.nih.gov/pubmed/27780305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13164
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