Mitomycin C treatment induces resistance and enhanced migration via phosphorylated Akt in aggressive lung cancer cells

Since 1984, mitomycin C (MMC) has been applied in the treatment of non-small-cell lung cancer (NSCLC). MMC-based chemotherapeutic regimens are still under consideration owing to the efficacy and low cost as compared with other second-line regimens in patients with advanced NSCLC. Hence, it is import...

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Udgivet i:Oncotarget
Main Authors: Shen, Cheng-Ying, Chen, Li-Han, Lin, Yu-Fen, Lai, Liang-Chuan, Chuang, Eric Y., Tsai, Mong-Hsun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346766/
https://ncbi.nlm.nih.gov/pubmed/27833080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13237
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