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GORAB promotes embryonic lung maturation through antagonizing AKT phosphorylation, versican expression and mesenchymal cell migration

Embryonic development of the alveolar sac of the lung is dependent upon multiple signaling pathways to coordinate cell growth, migration, and the formation of the extracellular matrix. Here, we identify GORAB as a regulator of embryonic alveolar sac formation as genetically disrupting the Gorab gene...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Liu, Ying, Chen, Xi, Choi, Yeon Ja, Yang, Ning, Song, Zhongya, Snedecor, Elizabeth R., Liang, Wei, Leung, Elaine Lai-Han, Zhang, Lianfeng, Qin, Chuan, Chen, Jiang
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319104/
https://ncbi.nlm.nih.gov/pubmed/32067289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902075R
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