Deubiquitinase USP9X deubiquitinates β-catenin and promotes high grade glioma cell growth

β-catenin is a crucial signal transduction molecule in the Wnt/β-catenin signal pathway, and increased β-catenin expression has consistently been found in high grade gliomas. However, the mechanisms responsible for β-catenin overexpression have remained elusive. Here we show that the deubiquitinase...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Yang, Bo, Zhang, Shiming, Wang, Zhihao, Yang, Chunxu, Ouyang, Wen, Zhou, Fuxiang, Zhou, Yunfeng, Xie, Conghua
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346732/
https://ncbi.nlm.nih.gov/pubmed/27783990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12819
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