MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway

Malignant fibrous histiocytoma amplified sequence 1 (MFHAS1) is a predicted oncoprotein that demonstrates tumorigenic activity in vivo; however, the mechanisms involved are unknown. Macrophages are divided into the pro-inflammatory M1 and anti-inflammatory/protumoral M2 subtypes. Tumor cells can ind...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Chen, Wankun, Xu, Yajun, Zhong, Jing, Wang, Huihui, Weng, Meilin, Cheng, Qian, Wu, Qichao, Sun, Zhirong, Jiang, Hui, Zhu, Minmin, Ren, Yu, Xu, Pingbo, Chen, Jiawei, Miao, Changhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346672/
https://ncbi.nlm.nih.gov/pubmed/27783989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12807
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