CCR10/CCL27 crosstalk contributes to failure of proteasome-inhibitors in multiple myeloma

The bone marrow microenvironment plays a decisive role in multiple myeloma progression and drug resistance. Chemokines are soluble mediators of cell migration, proliferation and survival and essentially modulate tumor progression and drug resistance. Here we investigated bone marrow-derived chemokin...

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Pubblicato in:Oncotarget
Autori principali: Thangavadivel, Shanmugapriya, Zelle-Rieser, Claudia, Olivier, Angelika, Postert, Benno, Untergasser, Gerold, Kern, Johann, Brunner, Andrea, Gunsilius, Eberhard, Biedermann, Rainer, Hajek, Roman, Pour, Ludek, Willenbacher, Wolfgang, Greil, Richard, Jöhrer, Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346663/
https://ncbi.nlm.nih.gov/pubmed/27732933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12522
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