T cells in multiple myeloma display features of exhaustion and senescence at the tumor site

BACKGROUND: Multiple myeloma is an incurable plasma cell malignancy that is mostly restricted to the bone marrow. Cancer-induced dysfunction of cytotoxic T cells at the tumor site may be responsible for immune evasion and therapeutical failure of immunotherapies. Therefore, enhanced knowledge about...

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Dades bibliogràfiques
Publicat a:J Hematol Oncol
Autors principals: Zelle-Rieser, Claudia, Thangavadivel, Shanmugapriya, Biedermann, Rainer, Brunner, Andrea, Stoitzner, Patrizia, Willenbacher, Ella, Greil, Richard, Jöhrer, Karin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093947/
https://ncbi.nlm.nih.gov/pubmed/27809856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0345-3
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