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Bigenic Cre/loxP, puΔtk conditional genetic ablation

Genetic ablation experiments are used to resolve problems regarding cell lineages and the in vivo function of certain groups of cells. We describe a two-component conditional ablation technology using a mouse carrying an X-linked puΔtk transgene, which is only activated in cells expressing Cre. Abla...

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Autori principali: Chen, You-Tzung, Levasseur, Regis, Vaishnav, Sukeshi, Karsenty, Gerard, Bradley, Allan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC534639/
https://ncbi.nlm.nih.gov/pubmed/15561996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh158
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