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CYP2A6 genetic variation alters striatal-cingulate circuits, network hubs and executive processing in smokers

BACKGROUND: Variation in the CYP2A6 gene alters the rate of nicotine metabolic inactivation and is associated with smoking behaviors and cessation success rates. The underlying neurobiological mechanisms of this genetic influence remain unknown. METHODS: Intrinsic functional connectivity strength (F...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biol Psychiatry
Auteurs principaux: Li, Sufang, Yang, Yihong, Hoffmann, Ewa, Tyndale, Rachel F., Stein, Elliot A.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346346/
https://ncbi.nlm.nih.gov/pubmed/27865452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.09.013
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