Cocaine use reverses striatal plasticity produced during cocaine-seeking

BACKGROUND: Relapse is a two-component process consisting of a highly motivated drug-seeking phase that, if successful, is followed by a drug-using phase resulting in temporary satiation. In rodents, cue-induced drug-seeking requires transient synaptic potentiation (t-SP) of cortical glutamatergic s...

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Udgivet i:Biol Psychiatry
Main Authors: Spencer, Sade, Garcia-Keller, Constanza, Roberts-Wolfe, Douglas, Heinsbroek, Jasper A., Mulvaney, Mallory, Sorrell, Anne, Kalivas, Peter W.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346331/
https://ncbi.nlm.nih.gov/pubmed/27837917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.08.033
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