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Defective Anks1a disrupts the export of receptor tyrosine kinases from the endoplasmic reticulum

EphA2 has been implicated in amplifying ErbB2 tumorigenic signaling. One protein that interacts with EphA2 is the Anks1a PTB adaptor. However, the precise role of Anks1a in EphA2-mediated tumorigenesis is unclear. We demonstrated that Anks1a localizes to the ER upon phosphorylation and that the Anky...

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Vydáno v:BMB Rep
Hlavní autor: Park, Soochul
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346308/
https://ncbi.nlm.nih.gov/pubmed/27802842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2016.49.12.186
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