Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom

Isolated populations with enrichment of variants due to recent population bottlenecks provide a powerful resource for identifying disease-associated genetic variants and genes. As a model of an isolate population, we sequenced the genomes of 1463 Finnish individuals as part of the Sequencing Initiat...

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Pubblicato in:Eur J Hum Genet
Autori principali: Chheda, Himanshu, Palta, Priit, Pirinen, Matti, McCarthy, Shane, Walter, Klaudia, Koskinen, Seppo, Salomaa, Veikko, Daly, Mark, Durbin, Richard, Palotie, Aarno, Aittokallio, Tero, Ripatti, Samuli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346294/
https://ncbi.nlm.nih.gov/pubmed/28145424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.205
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