Silencing markers are retained on pericentric heterochromatin during murine primordial germ cell development

BACKGROUND: In the nuclei of most mammalian cells, pericentric heterochromatin is characterized by DNA methylation, histone modifications such as H3K9me3 and H4K20me3, and specific binding proteins like heterochromatin-binding protein 1 isoforms (HP1 isoforms). Maintenance of this specialized chroma...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Magaraki, Aristea, van der Heijden, Godfried, Sleddens-Linkels, Esther, Magarakis, Leonidas, van Cappellen, Wiggert A., Peters, Antoine H. F. M., Gribnau, Joost, Baarends, Willy M., Eijpe, Maureen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346203/
https://ncbi.nlm.nih.gov/pubmed/28293300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-017-0119-3
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