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A physiological connection between tmRNA and peptidyl-tRNA hydrolase functions in Escherichia coli
The bacterial ssrA gene codes for a dual function RNA, tmRNA, which possesses tRNA-like and mRNA-like regions. The tmRNA appends an oligopeptide tag to the polypeptide on the P-site tRNA by a trans-translation process that rescues ribosomes stalled on the mRNAs and targets the aberrant protein for d...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC534616/ https://ncbi.nlm.nih.gov/pubmed/15547251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh924 |
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