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A physiological connection between tmRNA and peptidyl-tRNA hydrolase functions in Escherichia coli

The bacterial ssrA gene codes for a dual function RNA, tmRNA, which possesses tRNA-like and mRNA-like regions. The tmRNA appends an oligopeptide tag to the polypeptide on the P-site tRNA by a trans-translation process that rescues ribosomes stalled on the mRNAs and targets the aberrant protein for d...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Singh, Nongmaithem Sadananda, Varshney, Umesh
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534616/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15547251/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh924
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