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Oleate induces K(ATP) channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge

The unsaturated fatty acid, oleate exhibits anorexigenic properties reducing food intake and hepatic glucose output. However, its mechanism of action in the hypothalamus has not been fully determined. This study investigated the effects of oleate and glucose on GT1-7 mouse hypothalamic cells (a mode...

詳細記述

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書誌詳細
出版年:Neuroscience
主要な著者: Dadak, Selma, Beall, Craig, Vlachaki Walker, Julia M., Soutar, Marc P.M., McCrimmon, Rory J., Ashford, Michael L.J.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346158/
https://ncbi.nlm.nih.gov/pubmed/28087336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.12.053
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