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Oleate induces K(ATP) channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge

The unsaturated fatty acid, oleate exhibits anorexigenic properties reducing food intake and hepatic glucose output. However, its mechanism of action in the hypothalamus has not been fully determined. This study investigated the effects of oleate and glucose on GT1-7 mouse hypothalamic cells (a mode...

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Опубликовано в: :Neuroscience
Главные авторы: Dadak, Selma, Beall, Craig, Vlachaki Walker, Julia M., Soutar, Marc P.M., McCrimmon, Rory J., Ashford, Michael L.J.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346158/
https://ncbi.nlm.nih.gov/pubmed/28087336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.12.053
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