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Oleate induces K(ATP) channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge

The unsaturated fatty acid, oleate exhibits anorexigenic properties reducing food intake and hepatic glucose output. However, its mechanism of action in the hypothalamus has not been fully determined. This study investigated the effects of oleate and glucose on GT1-7 mouse hypothalamic cells (a mode...

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Bibliografiska uppgifter
I publikationen:Neuroscience
Huvudupphovsmän: Dadak, Selma, Beall, Craig, Vlachaki Walker, Julia M., Soutar, Marc P.M., McCrimmon, Rory J., Ashford, Michael L.J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier Science 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346158/
https://ncbi.nlm.nih.gov/pubmed/28087336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.12.053
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