Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability

Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophn1 affects neuronal development is only partly understood. Here we have exploited adult hippocampal neurogenesis to dissect the steps of neuronal differ...

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Gepubliceerd in:Neurobiol Dis
Hoofdauteurs: Allegra, Manuela, Spalletti, Cristina, Vignoli, Beatrice, Azzimondi, Stefano, Busti, Irene, Billuart, Pierre, Canossa, Marco, Caleo, Matteo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Academic Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346071/
https://ncbi.nlm.nih.gov/pubmed/28088401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.01.003
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