Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability

Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophn1 affects neuronal development is only partly understood. Here we have exploited adult hippocampal neurogenesis to dissect the steps of neuronal differ...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Allegra, Manuela, Spalletti, Cristina, Vignoli, Beatrice, Azzimondi, Stefano, Busti, Irene, Billuart, Pierre, Canossa, Marco, Caleo, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346071/
https://ncbi.nlm.nih.gov/pubmed/28088401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.01.003
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