Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability

Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophn1 affects neuronal development is only partly understood. Here we have exploited adult hippocampal neurogenesis to dissect the steps of neuronal differ...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Neurobiol Dis
Main Authors: Allegra, Manuela, Spalletti, Cristina, Vignoli, Beatrice, Azzimondi, Stefano, Busti, Irene, Billuart, Pierre, Canossa, Marco, Caleo, Matteo
Formato: Artigo
Idioma:Inglês
Publicado: Academic Press 2017
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346071/
https://ncbi.nlm.nih.gov/pubmed/28088401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.01.003
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares