Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability

Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophn1 affects neuronal development is only partly understood. Here we have exploited adult hippocampal neurogenesis to dissect the steps of neuronal differ...

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Bibliografiset tiedot
Julkaisussa:Neurobiol Dis
Päätekijät: Allegra, Manuela, Spalletti, Cristina, Vignoli, Beatrice, Azzimondi, Stefano, Busti, Irene, Billuart, Pierre, Canossa, Marco, Caleo, Matteo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Academic Press 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346071/
https://ncbi.nlm.nih.gov/pubmed/28088401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.01.003
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