Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability

Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophn1 affects neuronal development is only partly understood. Here we have exploited adult hippocampal neurogenesis to dissect the steps of neuronal differ...

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Bibliographic Details
Published in:Neurobiol Dis
Main Authors: Allegra, Manuela, Spalletti, Cristina, Vignoli, Beatrice, Azzimondi, Stefano, Busti, Irene, Billuart, Pierre, Canossa, Marco, Caleo, Matteo
Format: Artigo
Language:Inglês
Published: Academic Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346071/
https://ncbi.nlm.nih.gov/pubmed/28088401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.01.003
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