Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target

Expression of B7-H1, a costimulating glycoprotein in the B7 family, is normally restricted to macrophage-lineage cells, providing a potential costimulatory signal source for regulation of T cell activation. In contrast, aberrant expression of B7-H1 by tumor cells has been implicated in impairment of...

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Bibliografiske detaljer
Main Authors: Thompson, R. Houston, Gillett, Michael D., Cheville, John C., Lohse, Christine M., Dong, Haidong, Webster, W. Scott, Krejci, Kent G., Lobo, John R., Sengupta, Shomik, Chen, Lieping, Zincke, Horst, Blute, Michael L., Strome, Scott E., Leibovich, Bradley C., Kwon, Eugene D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC534606/
https://ncbi.nlm.nih.gov/pubmed/15569934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406351101
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