Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target

Expression of B7-H1, a costimulating glycoprotein in the B7 family, is normally restricted to macrophage-lineage cells, providing a potential costimulatory signal source for regulation of T cell activation. In contrast, aberrant expression of B7-H1 by tumor cells has been implicated in impairment of...

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Detalhes bibliográficos
Main Authors: Thompson, R. Houston, Gillett, Michael D., Cheville, John C., Lohse, Christine M., Dong, Haidong, Webster, W. Scott, Krejci, Kent G., Lobo, John R., Sengupta, Shomik, Chen, Lieping, Zincke, Horst, Blute, Michael L., Strome, Scott E., Leibovich, Bradley C., Kwon, Eugene D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC534606/
https://ncbi.nlm.nih.gov/pubmed/15569934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406351101
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