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HK2 Recruitment to Phospho-BAD Prevents Its Degradation, Promoting Warburg Glycolysis by Theileria-Transformed Leukocytes

Theileria annulata infects bovine leukocytes, transforming them into invasive, cancer-like cells that cause the widespread disease called tropical theileriosis. We report that in Theileria-transformed leukocytes hexokinase-2 (HK2) binds to B cell lymphoma-2-associated death promoter (BAD) only when...

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Bibliografiske detaljer
Udgivet i:ACS Infect Dis
Main Authors: Haidar, Malak, Lombès, Anne, Bouillaud, Frédéric, Kennedy, Eileen J., Langsley, Gordon
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346052/
https://ncbi.nlm.nih.gov/pubmed/28086019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00180
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