Reactivating p53 and Inducing Tumor Apoptosis (RITA) Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin

Colorectal carcinoma (CRC) is the most common cancer of the gastrointestinal tract with frequently dysregulated intracellular signaling pathways, including p53 signaling. The mainstay of chemotherapy treatment of CRC is 5-fluorouracil (5FU) and oxaliplatin. The two anticancer drugs mediate their the...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Wiegering, Armin, Matthes, Niels, Mühling, Bettina, Koospal, Monika, Quenzer, Anne, Peter, Stephanie, Germer, Christoph-Thomas, Linnebacher, Michael, Otto, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2017
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345961/
https://ncbi.nlm.nih.gov/pubmed/28284059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.01.007
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