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Coffee extract inhibits adipogenesis in 3T3-L1 preadipocyes by interrupting insulin signaling through the downregulation of IRS1

Although epidemiological data have indicated that a strong negative association exists between coffee consumption and the prevalence of obesity-associated diseases, the molecular mechanisms by which coffee intake prevents obesity-associated diseases has not yet been elucidated. In this study, we fou...

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Veröffentlicht in:PLoS One
Hauptverfasser: Maki, Chihiro, Funakoshi-Tago, Megumi, Aoyagi, Ryohei, Ueda, Fumihito, Kimura, Masaki, Kobata, Kenji, Tago, Kenji, Tamura, Hiroomi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345824/
https://ncbi.nlm.nih.gov/pubmed/28282409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173264
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