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Comparative Analysis of Human Nucleoside Kinase-Based Reporter Systems for PET Imaging

PURPOSE: Radionuclide-based reporter gene imaging has the sensitivity to monitor gene- and cell-based therapies in human subjects. Potential immunogenicity of current viral transgenes warrants development of human-based reporter systems. We compared human nucleoside kinase reporters to a panel of nu...

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Bibliografiske detaljer
Udgivet i:Mol Imaging Biol
Main Authors: Lee, Jason T., Zhang, Hanwen, Moroz, Maxim A., Likar, Yury, Shenker, Larissa, Sumzin, Nikita, Lobo, Jose, Zurita, Juan, Collins, Jeffrey, van Dam, R. Michael, Ponomarev, Vladimir
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345744/
https://ncbi.nlm.nih.gov/pubmed/27393689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-016-0981-6
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