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A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans

When mutations have small effects on fitness, population size plays an important role in determining the amount and nature of deleterious genetic variation. The extent to which recent population size changes have impacted deleterious variation in humans has been a question of considerable interest a...

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書目詳細資料
發表在:G3 (Bethesda)
Main Authors: Koch, Evan, Novembre, John
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345704/
https://ncbi.nlm.nih.gov/pubmed/28159863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.039651
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