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A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans

When mutations have small effects on fitness, population size plays an important role in determining the amount and nature of deleterious genetic variation. The extent to which recent population size changes have impacted deleterious variation in humans has been a question of considerable interest a...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Koch, Evan, Novembre, John
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345704/
https://ncbi.nlm.nih.gov/pubmed/28159863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.039651
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