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Brain‐derived neurotrophic factor attenuates doxorubicin‐induced cardiac dysfunction through activating Akt signalling in rats

The clinical application of doxorubicin (Dox) is limited by its adverse effect of cardiotoxicity. Previous studies have suggested the cardioprotective effect of brain‐derived neurotrophic factor (BDNF). We hypothesize that BDNF could protect against Dox‐induced cardiotoxicity. Sprague Dawley rats we...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Hang, Pengzhou, Zhao, Jing, Sun, Li, Li, Minghui, Han, Yu, Du, Zhimin, Li, Yue
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345637/
https://ncbi.nlm.nih.gov/pubmed/28098423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13012
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