Choline Attenuates Cardiac Fibrosis by Inhibiting p38MAPK Signaling Possibly by Acting on M(3) Muscarinic Acetylcholine Receptor

Choline has been reported to produce a variety of cellular functions including cardioprotection via activating M(3) muscarinic acetylcholine receptor (M(3)R) under various insults. However, whether choline offers similar beneficial effects via the same mechanism in cardiac fibrosis remained unexplor...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhao, Lihui, Chen, Tingting, Hang, Pengzhou, Li, Wen, Guo, Jing, Pan, Yang, Du, Jingjing, Zheng, Yuyang, Du, Zhimin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900736/
https://ncbi.nlm.nih.gov/pubmed/31849653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01386
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