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Potent effects of dioscin against pancreatic cancer via miR‐149‐3P‐mediated inhibition of the Akt1 signalling pathway

BACKGROUND AND PURPOSE: The aim of the present study was to investigate the effects and possible underlying mechanisms of dioscin against pancreatic cancer in vitro and in vivo. EXPERIMENTAL APPROACH: In vitro actions of dioscin on viability of ASPC‐1 and PANC‐1 cells, and in vivo effects to suppres...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Si, Lingling, Xu, Lina, Yin, Lianhong, Qi, Yan, Han, Xu, Xu, Youwei, Zhao, Yanyan, Liu, Kexin, Peng, Jinyong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345629/
https://ncbi.nlm.nih.gov/pubmed/28095588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13718
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