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Mechanotransduction and strain amplification in osteocyte cell processes

A paradox in bone tissue is that tissue-level strains due to animal and human locomotion are too small to initiate intracellular chemical responses directly. A model recently was proposed to resolve this paradox, which predicts that the fluid flow through the pericellular matrix in the lacunar-canal...

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Bibliographic Details
Main Authors: Han, Yuefeng, Cowin, Stephen C., Schaffler, Mitchell B., Weinbaum, Sheldon
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC534548/
https://ncbi.nlm.nih.gov/pubmed/15539460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407429101
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