3-hydroxy-3-methylglutaryl–CoA synthase intermediate complex observed in “real-time”

The formation of carbon–carbon bonds via an acyl-enzyme intermediate plays a central role in fatty acid, polyketide, and isoprenoid biosynthesis. Uniquely among condensing enzymes, 3-hydroxy-3-methylglutaryl (HMG)–CoA synthase (HMGS) catalyzes the formation of a carbon–carbon bond by activating the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Theisen, Michael J., Misra, Ila, Saadat, Dana, Campobasso, Nino, Miziorko, Henry M., Harrison, David H. T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC534525/
https://ncbi.nlm.nih.gov/pubmed/15498869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405809101
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