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3-hydroxy-3-methylglutaryl–CoA synthase intermediate complex observed in “real-time”
The formation of carbon–carbon bonds via an acyl-enzyme intermediate plays a central role in fatty acid, polyketide, and isoprenoid biosynthesis. Uniquely among condensing enzymes, 3-hydroxy-3-methylglutaryl (HMG)–CoA synthase (HMGS) catalyzes the formation of a carbon–carbon bond by activating the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC534525/ https://ncbi.nlm.nih.gov/pubmed/15498869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405809101 |
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